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Low white blood cell count

Find out about low white blood cell count. It usually means your body is not making enough white blood cells and can increase your risk of getting infections.

About this information

This NHS content is written for people in England. Services, entitlements and contact routes may differ in other countries.

How you get a low white blood cell count

Common causes of a low white blood cell count include:

Agranulocytosis and neutropenia are conditions that cause a low white blood cell count.

Symptoms of a low white blood cell count

A low white blood cell count does not always cause any symptoms.

The main symptom is getting frequent infections. Signs of an infection may include:

  • a high temperature, or feeling hot, cold or shivery
  • sore throat
  • mouth sores that keep coming back
  • toothache
  • skin rashes
  • tiredness
  • flu-like symptoms

A blood test can tell you if your white blood cell count is low.

Treatment for a low white blood cell count

Treatment for a low white blood cell count depends on what's causing it. Treatment often includes antibiotics.

If it's caused by a medicine or other treatment you're having, you may need to stop the treatment or change your dose.

You may also need specific treatment:

  • to boost your white blood cells
  • if you've got an infection

Occasionally, infections can lead to a life-threatening condition called sepsis.

See a GP if:

  • you know you're at risk of a low white blood cell count and you get an infection
  • you keep getting infections

Things you can do to avoid infections

If you have a low white blood cell count caused by illness, cancer treatment or medicine, it's important to take steps to avoid infections.

Do

  • avoid close contact with people who are sick

  • store and prepare food properly to avoid food poisoning

  • wash your hands with soap and warm water regularly

  • use an electric shaver instead of a razor

  • avoid shared hot tubs

Don't

  • do not share food, cups, utensils, toothbrushes or make-up

  • do not eat raw foods like meat, shellfish and eggs

  • do not change cat litter or handle animal poo

  • do not change nappies

  • do not walk outside barefoot

  • do not swim in ponds, lakes and rivers

Low white blood cell count

Causes

Low white blood cell count

Symptoms

Low white blood cell count

Medical treatments

Low white blood cell count

Self-care

Causes of a low white blood cell count include some cancers or cancer treatments, taking some medicines, and autoimmune conditions.

A low white blood cell count can cause frequent infections. Signs of an infection include a high temperature, sore throat and flu-like symptoms.

Treatment for a low white blood cell count depends on the cause. It's often treated with antibiotics.

If you have a low white blood cell count you can lower your chances of infections by avoiding people who are sick and trying to avoid food poisoning.

Content supplied by the NHS website

Content supplied by the NHS website, refreshed 19 August 2026. View the original NHS article ↗

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