This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.
Pepto-Bismol (bismuth subsalicylate)
What it's forPepto-Bismol (bismuth subsalicylate)
How it's used (previously Dosage and administration)Pepto-Bismol (bismuth subsalicylate)
Side effectsPepto-Bismol (bismuth subsalicylate)
Who it's forPepto-Bismol (bismuth subsalicylate)
InteractionsPepto-Bismol (bismuth subsalicylate) is used to treat symptoms such as indigestion, heartburn, feeling sick (nausea) and diarrhoea.
Pepto-Bismol (bismuth subsalicylate) comes as a liquid you swallow or chewable tablets. Always follow the instructions that come with your medicine.
Side effects of Pepto-Bismol (bismuth subsalicylate) include black poo and a black tongue. More serious side effects are rare.
Pepto-Bismol (bismuth subsalicylate) is suitable for most people aged 16 years or older, but always check before taking it.
Taking Pepto-Bismol (bismuth subsalicylate) with some medicines, like aspirin and anticoagulants, can cause problems. Always check before taking it.
What Pepto-Bismol is for
Pepto-Bismol (bismuth subsalicylate) is used to treat symptoms such as:
- indigestion
- acid reflux and heartburn
- feeling sick (nausea)
- diarrhoea
It works by reducing inflammation and forming a protective coating in your stomach, the lower part of your food pipe and your gut.
How to take Pepto-Bismol
Pepto-Bismol (bismuth subsalicylate) usually comes as a liquid you swallow or tablets you chew. You can take it with or without food.
Always check the packet or leaflet that comes with your medicine. Ask a pharmacist or doctor for advice if you're not sure how to take it or have any problems taking it.
How to take different types of Pepto-Bismol
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Do not take Pepto-Bismol for more than 2 days unless advised to by a doctor.
Stop taking it and see a GP if your symptoms get worse or do not get better.
If you take too much Pepto-Bismol
Taking an extra dose of Pepto-Bismol is unlikely to cause problems, but it's important to get medical advice if you take too much as it can be dangerous.
Speak to a pharmacist as soon as possible if:
- you've taken more Pepto-Bismol than it says on the packet or leaflet
- you're taking Pepto-Bismol and start hearing ringing or buzzing in your ears (tinnitus)
If you're unable to speak to a pharmacist, or you took too much of your medicine on purpose, call NHS 111 for advice.
Find a pharmacyInformation
If you're told to go to A&E, do not drive. Ask someone to drive you or call 999 and ask for an ambulance.
Bring the Pepto-Bismol packet or leaflet inside it, any remaining medicine, and any other medicines you take.
Side effects of Pepto-Bismol
Like all medicines, Pepto-Bismol (bismuth subsalicylate) can cause side effects, although not everyone gets them.
Common side effects
Possible side effects of Pepto-Bismol include:
- black poo
- a black tongue
These side effects are harmless and usually go away on their own.
Pepto-Bismol will not usually affect your ability to drive, ride a bike or use machinery.
Speak to a pharmacist or doctor if:
- you have any side effects that bother you or do not go away
They may be able to give you advice about how to reduce any side effects.
Find a pharmacySerious side effects
In rare cases, Pepto-Bismol can cause a serious allergic reaction.
Symptoms of an allergic reaction (anaphylaxis) include a swollen throat or tongue, a raised, itchy rash and difficulty breathing.
Call 999 if:
- you're taking Pepto-Bismol and think you might be having anaphylaxis
Who can and cannot take Pepto-Bismol
Most people aged 16 years or older can take Pepto-Bismol (bismuth subsalicylate).
Do not give Pepto-Bismol to children aged 15 years or under because it can cause a serious condition called Reye's syndrome in rare cases.
Pepto-Bismol is not suitable for everyone. For example, it may not be suitable if you:
- have had an allergic reaction or serious side effect from bismuth subsalicylate before
- have had an allergic reaction or serious side effect from aspirin before
- have blood in your poo
- have a blood clotting disorder
- have gout
- have a stomach ulcer
Check the packet or leaflet that comes with your medicine to see if it's suitable for you. Speak to a pharmacist or doctor if you're not sure if you can use it.
Breastfeeding and Pepto-Bismol
Pepto-Bismol is not usually recommended if you're breastfeeding.
Check with a pharmacist or doctor before using Pepto-Bismol while you're breastfeeding. They may be able to recommend a different medicine.
Pregnancy and Pepto-Bismol
Pepto-Bismol is not usually recommended during pregnancy.
Talk to a doctor or pharmacist before taking Pepto-Bismol while you're pregnant. They may be able to recommend a different medicine.
Taking Pepto-Bismol with other medicines, food and drink
There are some medicines, remedies and supplements that may not mix well with Pepto-Bismol (bismuth subsalicylate).
These include:
- non-steroidal anti-inflammatory drugs (NSAIDs), such as aspirin and ibuprofen
- anticoagulants, such as warfarin and apixaban
- methotrexate, a medicine for rheumatoid arthritis, psoriasis or cancer
- some antibiotics, such as doxycycline
- some antidepressants
- some medicines for gout
- some medicines for diabetes
Check the packet or leaflet that comes with your medicine to see if it's suitable for you. Speak to a pharmacist or doctor if you're not sure if you can take it.
Food, drink and alcohol with Pepto-Bismol
You can eat and drink as usual when taking Pepto-Bismol.
Content supplied by the NHS website, refreshed 12 October 2026. View the original NHS article ↗
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