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Detailed medicine guidance

Pregnancy, breastfeeding and fertility while taking allopurinol

NHS medicines information on allopurinol and whether you can take it while pregnant or breastfeeding.

About this information

This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.

Allopurinol and pregnancy

Allopurinol is not usually recommended during pregnancy. There is not enough evidence to say that it's safe.

Talk to a doctor if you're thinking about trying for a baby. There may be other medicines that are more suitable for you to take during pregnancy.

Allopurinol and breastfeeding

If your doctor or health visitor says your baby is healthy, you can take allopurinol while you're breastfeeding.

There is not much information about using allopurinol while breastfeeding, but it is likely that allopurinol passes into breast milk in small amounts

If you notice that your baby is not feeding as well as usual, is being sick (vomiting), has diarrhoea or a rash, or if you have any other concerns about your baby, then talk to your doctor, pharmacist, midwife or health visitor.

Allopurinol and fertility

There is no evidence to suggest that taking allopurinol reduces fertility in either men or women. However, talk to a doctor if you want to try for a baby while taking allopurinol.

Meds New IA (H2) - Pregnancy non-urgent care card

Tell your doctor if you're:

  • trying to get pregnant
  • pregnant
  • breastfeeding

View the original NHS website page ↗. Refreshed 19 August 2026.

Licensed under the Open Government Licence v3.0 ↗. MyPHU is independent and is not endorsed by the NHS.

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