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Detailed medicine guidance

Taking carvedilol with other medicines and herbal supplements

NHS medicines information on possible interactions with carvedilol and other medicines, herbal remedies and supplements.

About this information

This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.

Cautions with other medicines

There are some medicines that can affect the way carvedilol works.

Tell your doctor if you're taking:

  • other medicines for high blood pressure – when taken together with carvedilol, they can sometimes lower your blood pressure too much
  • other medicines that can lower your blood pressure – these include some antidepressants, nitrates (for chest pain), baclofen (a muscle relaxant), medicines for an enlarged prostate gland like tamsulosin, or levodopa (for Parkinson's disease)
  • medicines for an irregular heartbeat such as digoxin, amiodarone or flecainide
  • medicines for asthma or chronic obstructive pulmonary disease (COPD)
  • medicines for diabetes, particularly insulin – carvedilol may lower your blood sugar too much when taken with diabetes medicines, and may make it more difficult to recognise the warning signs of low blood sugar. Speak to your doctor if you have low blood sugar levels without getting any warning signs. Check your blood sugar after exercise, and follow usual advice about checking it before driving, or operating machinery
  • medicines that treat nose or sinus congestion, or other cold remedies (including those you can buy in the pharmacy)
  • medicines for allergies, such as ephedrine, noradrenaline or adrenaline
  • non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, diclofenac or naproxen – these medicines may increase your blood pressure
  • ciclosporin, used for immune conditions such as rheumatoid arthritis

View the original NHS website page ↗. Refreshed 19 August 2026.

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