Taking clonidine with other medicines and herbal supplements

There are some medicines that may increase the risk of side effects with clonidine or affect how well it works.

Tell your doctor or pharmacist if you're taking:

• other vasodilator medicines such as diazoxide or sodium nitroprusside
• medicines used to treat high blood pressure or heart problems, including diclofenac, digoxin, beta blockers such as propranolol, atenolol, bisoprolol or carvedilol, or calcium channel blockers such as diltiazem or verapamil – taking clonidine with these can sometimes lower your blood pressure or slow your heartbeat (pulse) too much
• medicines for an enlarged prostate
• medicines that make you pee more (diuretics)
• medicines for mental health problems, including antidepressants or antipsychotics
• medicines for Parkinson’s disease such as levodopa
• muscle relaxants such as baclofen or tizanidine
• medicines that make you sleepy such as anti-anxiety medicines or sleeping tablets
• non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, naproxen, diclofenac, celecoxib or etoricoxib
• methylphenidate, for attention deficit hyperactivity disorder (ADHD)

There's not enough information to say that complementary medicines and herbal remedies are safe to take with clonidine. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.

Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.