Taking co-codamol for adults with other medicines and herbal supplements

Some medicines affect the way co-codamol works. Co-codamol can also stop some medicines working as well as they should.

Tell your doctor if you're taking:

• sleeping pills or tranquillisers – particularly benzodiazepines such as diazepam, temazepam or lorazepam
• antidepressants – some types do not mix with co-codamol
• medicines to stop you feeling or being sick such as domperidone or metoclopramide
• medicines that help to prevent blood clots (anticoagulants) such as warfarin
• medicines to treat infections, particularly rifampicin or ciprofloxacin
• epilepsy medicines

It's safe to take co-codamol with ibuprofen and aspirin.

Do not take co-codamol with paracetamol, or other medicines that contain paracetamol, unless you've been advised to by a doctor. Co-codamol already contains paracetamol so you could be at risk of paracetamol overdose.

Medicines that have paracetamol in them include painkillers like Tramacet and co-dydramol, migraine remedies, and some cough and cold remedies like Lemsip and Night Nurse.

Before taking co-codamol with any other medicines, check the label to see whether they contain paracetamol.

There's not enough information to say that complementary medicines, herbal remedies and supplements are safe to take with co-codamol.

They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.

Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.