This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.
Cautions with other medicines
Other medicines will not usually affect how medroxyprogesterone contraceptive injections work.
But tell your nurse or doctor when you go for the injection if you're taking other medicines. You can also talk to a pharmacist.
Mixing medroxyprogesterone contraceptive injections with herbal remedies and supplementsDo not take St John's wort, a herbal remedy used for depression, with medroxyprogesterone contraceptive injections. It can affect the way medroxyprogesterone works.
There's not enough information to say that other complementary medicines, herbal remedies and supplements are safe to take with medroxyprogesterone contraceptive injections. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.
Meds New IA (H2) - Cautions with other medicines alert
Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.
View the original NHS website page ↗. Refreshed 19 August 2026.
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