Need emergency help? Call 999 in United Kingdom.

Open local help

Detailed medicine guidance

Taking cyclizine with other medicines and herbal supplements

NHS medicines information on possible interactions with cyclizine and other medicines, herbal remedies and supplements.

About this information

This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.

Cautions with other medicines

Some medicines can affect the way cyclizine works and increase the chance of having side effects.

Tell your pharmacist or doctor if you're taking:

  • a type of antidepressant called a monoamine oxidase inhibitor, such as phenelzine
  • any medicine that makes you drowsy, gives you a dry mouth or makes it difficult for you to pee – taking cyclizine might make these side effects worse
Taking cyclizine with other anti-sickness medicines

It's usually best to only take 1 type of medicine for feeling or being sick.

If cyclizine does not work for you, speak to your doctor and they may suggest a different medicine for you.

Mixing cyclizine with herbal remedies and supplements

Some herbal remedies can make your side effects worse. Speak to your pharmacist before taking any herbal remedies or supplements.

Meds New IA (H2) - Cautions with other medicines alert

Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.

View the original NHS website page ↗. Refreshed 19 August 2026.

Licensed under the Open Government Licence v3.0 ↗. MyPHU is independent and is not endorsed by the NHS.

More about Cyclizine