This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.
Cautions with other medicines
Some medicines may affect how gabapentin works or increase the chance of you having side effects.
Antacids can reduce the amount of gabapentin that the body takes in so it does not work as well.
To stop this happening, if you need to take an antacid, take it at least 2 hours before or after your dose of gabapentin.
Check with a pharmacist or your doctor if you're taking any other medicines, including:
- strong painkillers, such as morphine – these can make you very tired and dizzy when you start taking gabapentin
- antidepressants, such as amitriptyline or fluoxetine
- antipsychotic medicines for mental health problems like schizophrenia or bipolar disorder, such as olanzapine
These are not all the medicines that may cause problems if you take them with gabapentin. For a full list, see the leaflet inside your medicine packet.
View the original NHS website page ↗. Refreshed 19 August 2026.
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