Taking letrozole with other medicines and herbal supplements

Letrozole should not be taken with medicines for menopause symptoms, like hormone replacement therapy (HRT). These may contain ingredients similar to the hormone oestrogen. This could stop letrozole working as well as it should in treating your cancer.

It is OK to take letrozole with most other medicines.

Do not take any herbal remedies or supplements for menopause symptoms while taking letrozole. These can stop letrozole working as well as it should.

There's not enough information to say that other complementary medicines, herbal remedies and supplements are safe to take with letrozole. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.

Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.