This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.
Cautions with other medicines
Some medicines affect how loratadine works or can increase the chances of you having side effects.
Tell your doctor if you're taking:
- amiodarone, a medicine used to treat an irregular heartbeat
- cimetidine, an indigestion medicine
- erythromycin, an antibiotic
- any medicine that makes you feel sleepy, gives you a dry mouth or makes it difficult for you to pee – taking loratadine might make these side effects worse
Taking it with painkillers
You can take loratadine together with painkillers such as paracetamol or ibuprofen.
View the original NHS website page ↗. Refreshed 19 August 2026.
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