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Detailed medicine guidance

Who can and cannot take methylphenidate for adults

NHS medicines information on who can take methylphenidate and who may not be able to take it.

About this information

This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.

Who can take methylphenidate

Most adults can take methylphenidate.

Who may not be able to take methylphenidate

Methylphenidate is not suitable for some people.

Check with your doctor or pharmacist before starting to take it if you:

  • have ever had an allergic reaction to methylphenidate or any other medicine
  • have difficulty swallowing – some brands may not be suitable for you
  • have heart problems
  • have an overactive thyroid
  • have a tumour in the adrenal gland (phaeochromocytoma)
  • have mental health problems (or a close family member has mental health problems)
  • have high blood pressure or problems with your blood vessels, such as vasculitis
  • have epilepsy
  • have tics (sudden muscle twitches of the face or body), or a family history of Tourette's syndrome
  • have glaucoma or are at risk of getting glaucoma
  • are trying to get pregnant, are already pregnant or breastfeeding
  • have problems with drugs or alcohol

View the original NHS website page ↗. Refreshed 19 August 2026.

Licensed under the Open Government Licence v3.0 ↗. MyPHU is independent and is not endorsed by the NHS.

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