Taking nefopam with other medicines and herbal supplements

Some medicines and nefopam can affect each other and make it more likely that you will have side effects.

Tell your doctor if you're taking any of these medicines before you start taking nefopam:

• some types of antidepressants, such as phenelzine, isocarboxazid or tranylcypromine, which belong to a group called monoamine oxidase inhibitors, or amitriptyline, which belongs to the tricyclic antidepressant group
• any medicine that makes you sleepy, gives you a dry mouth, or makes it difficult for you to pee, including some antihistamines and antidepressants, as taking nefopam might make these side effects worse

You can take nefopam with everyday painkillers, such as paracetamol, or non-steroidal anti-inflammatory drugs (NSAIDs), like ibuprofen or naproxen.

Some opioid painkillers (like codeine, dihydrocodeine and morphine) have similar side effects to nefopam. This means if you take them together you're more likely to get more side effects such as feeling sick, confusion or feeling dizzy.

Speak to your doctor or pharmacist before taking any other painkillers along with nefopam.

There might be a problem taking some herbal remedies and supplements alongside nefopam, especially ones that cause sleepiness, a dry mouth or make it difficult to pee. Ask your pharmacist for advice.

It's not possible to say that other herbal remedies, vitamins and supplements are safe to take with nefopam. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.

Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.