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Detailed medicine guidance

Taking pantoprazole with other medicines and herbal supplements

NHS medicines information on possible interactions with pantoprazole and other medicines, herbal remedies and supplements.

About this information

This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.

Cautions with other medicines

Some medicines and pantoprazole can affect each other and make you more likely to have side effects or stop one of the medicines working as well.

Tell your doctor before starting to take pantoprazole if you're taking any other medicines, including:

  • antifungal medicines such as itraconazole, posaconazole or voriconazole
  • methotrexate, a medicine used to treat cancer, psoriasis and rheumatoid arthritis
  • HIV medicines
  • rifampicin, an antibiotic
  • medicines that help to prevent blood clots, such as warfarin

These are not all the medicines that may cause problems if you take them with pantoprazole. For a full list, see the leaflet inside your medicine packet.

View the original NHS website page ↗. Refreshed 19 August 2026.

Licensed under the Open Government Licence v3.0 ↗. MyPHU is independent and is not endorsed by the NHS.

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