This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.
Dosage and how to take promethazine
Dosage and strength
Promethazine tablets come in strengths of 10mg, 20mg or 25mg.
The liquid contains 5mg of promethazine in 5ml.
If you're taking liquid promethazine, follow the instructions that come with the medicine for how much to take.
For adults and children aged 10 years or older, your dose depends on why you're taking it.
For hay fever or hives the dose can vary from 10mg twice a day to 20mg 3 times a day or 25mg once or twice a day.
For preventing motion sickness you'll usually take 25mg the night before your journey. Some products only need to be taken 1 to 2 hours before travelling, if it's a short journey.
For treating motion sickness take 25mg as soon as possible and 25mg the same evening. You can then take 25mg the following evening, if you need it.
For vertigo the dose can vary from 25mg a day to 25mg 4 times a day.
Doses are lower for children aged 9 years or under. To find out what dose to give your child, ask your doctor or pharmacist for advice or check the medicine packet.
Dosage for promethazine mixed with other medicines
Promethazine can come mixed with other medicines, such as paracetamol. This is usually used to treat cough and cold symptoms. Your dose will depend on the type of medicine you're taking.
Check the instructions on the packaging for how much to take. Ask your pharmacist or doctor if you're unsure.
How to take it
You can take promethazine with or without food.
How to take tablets
Always take your promethazine tablets with a drink of water. Swallow them whole. Do not chew them.
How to take liquid
Liquid medicines containing promethazine come with a plastic syringe or spoon to help you measure out the right dose.
If you do not have a syringe or spoon, ask your pharmacist for one. Do not use a kitchen teaspoon as it will not measure the right amount.
View the original NHS website page ↗. Refreshed 19 August 2026.
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