This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.
Cautions with other medicines
Simeticone is generally safe to take with other medicines.
However, talk to a doctor or pharmacist before you take simeticone if you are taking levothyroxine for thyroid problems. Simeticone might stop levothyroxine being absorbed properly, meaning it will not work as well.
If the medicine contains other ingredients with simeticone, check the leaflet or talk to a doctor or pharmacist to make sure you can take it with other medicines.
Mixing simeticone with herbal remedies and supplementsThere's not enough information to say that complementary medicines, herbal remedies and supplements are safe to take with simeticone. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.
Meds New IA (H2) - Cautions with other medicines alert
Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.
View the original NHS website page ↗. Refreshed 19 August 2026.
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