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Detailed medicine guidance

Pregnancy, breastfeeding and fertility while taking sitagliptin

NHS medicines information on sitagliptin and whether you can take it while pregnant or breastfeeding.

About this information

This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.

Sitagliptin and pregnancy

Sitagliptin is not recommended in pregnancy as there is little information about whether it may affect a developing baby.

If you are pregnant or thinking of getting pregnant, talk to your doctor as they will need to review your treatment. They will be able to suggest a different medicine that is safer for you to take in pregnancy.

Sitagliptin and breastfeeding

Sitagliptin is not usually recommended while you're breastfeeding. We do not know how much of it passes into breast milk, but it is likely to be a fairly small amount.

If you are breastfeeding, or planning to breastfeed, talk to your doctor about what's best for you and your baby. They will need to review your treatment and may be able to suggest a different medicine for you, particularly if you're breastfeeding a newborn or premature baby.

If your doctor says it's OK to keep breastfeeding, contact your health visitor, midwife, pharmacist or doctor as soon as possible if:

  • your baby is not feeding as well as usual
  • your baby seems unusually sleepy or drowsy
  • your baby seems unusually restless or irritable
  • your baby is paler, or more sweaty, than usual
  • your baby seems hungrier than usual
  • your baby is peeing more
  • you have any other concerns about your baby
Sitagliptin and fertility

There's no evidence to suggest that taking sitagliptin reduces fertility in either men or women.

Speak to a pharmacist or your doctor if you're trying to get pregnant. They may want to review your treatment.

Meds New IA (H2) - Pregnancy non-urgent care card

Tell your doctor if you're:

  • trying to get pregnant
  • pregnant
  • breastfeeding

View the original NHS website page ↗. Refreshed 19 August 2026.

Licensed under the Open Government Licence v3.0 ↗. MyPHU is independent and is not endorsed by the NHS.

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