This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.
Cautions with other medicines
There are some medicines that may affect how sodium valproate works. Sodium valproate can also affect the way other medicines work.
Tell your doctor if you're taking any other medicines, including:
- any other medicines for epilepsy such as carbamazepine
- medicines for preventing blood clots such as warfarin
- aspirin
- cimetidine, a medicine for stomach ulcers
- medicines to treat HIV and AIDS such as ritonavir
- antibiotics such as erythromycin
- medicines for depression or other mental health problems, such as venlafaxine, quetiapine or diazepam
- cholesterol-lowering medicines such as cholestyramine
- medicines to prevent malaria such as mefloquine or chloroquine
These are not all the medicines that may cause problems if you take them with sodium valproate. For a full list, see the leaflet inside your medicine packet.
View the original NHS website page ↗. Refreshed 19 August 2026.
Licensed under the Open Government Licence v3.0 ↗. MyPHU is independent and is not endorsed by the NHS.