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Detailed medicine guidance

How and when to take zolpidem

NHS medicines information on dosage for zolpidem, how to take it and what to do if you miss a dose or take too much.

About this information

This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.

Dosage and strength

Zolpidem tablets come in 2 different strengths: 5mg and 10mg.

The usual dose is one 10mg tablet, taken just before you go to bed. It takes around 30 minutes to work.

If you're 65 years old or over, or if you have kidney or liver problems, your doctor may start you on a lower dose of 5mg.

Important

Do not take more than your prescribed dose of zolpidem.

How to take it

It's important to take zolpidem exactly as your doctor tells you. Your doctor might ask you to take a tablet on only 2 or 3 nights of the week, rather than every night.

Swallow the tablet whole with a drink of water. Do not crush or chew it.

You can take zolpidem with or without food.

How long to take it for

You'll usually be prescribed zolpidem for 2 days to 4 weeks.

It's only prescribed for a short period because your body gets used to this medicine quickly. After taking it for a few weeks, it's unlikely to have the same effect. Your body can also become dependent on it.

If you still have problems sleeping after you finish your course of zolpidem, try lifestyle changes for insomnia such as taking a warm bath before bed and not napping during the day. See your doctor again if these changes do not help.

If you forget to take it

If you forget to take your zolpidem, leave out the missed dose. Start again the next night and take your zolpidem at the usual time.

Never take 2 doses at the same time. Never take an extra dose to make up for a forgotten one.

If you take too much

Taking more than your prescribed dose of zolpidem can be dangerous. You may get symptoms including:

  • feeling drowsy, feeling confused, sleeping deeply and possibly going into a coma
  • feeling dizzy, light-headed or faint due to low blood pressure
  • floppy muscles
  • falling over or losing your balance
  • shallow breathing or difficulty breathing

Contact 111 for advice now if:

  • you take more than your prescribed dose of zolpidem – even if you do not feel any different

Go to 111.nhs.uk or call 111

Information

If you need to go to A&E, do not drive. Ask someone to drive you or call 999 and ask for an ambulance.

Bring the zolpidem packet or leaflet inside it, any remaining medicine, and any other medicines you take.

View the original NHS website page ↗. Refreshed 19 August 2026.

Licensed under the Open Government Licence v3.0 ↗. MyPHU is independent and is not endorsed by the NHS.

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