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Detailed medicine guidance

Who can and cannot use fentanyl

NHS medicines information on who can use fentanyl and who may not be able to use it.

About this information

This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.

Who can use fentanyl

Most adults can use fentanyl.

Some patches can be used by children aged 2 years old and over. However, young children and older people are more likely to get side effects.

Fentanyl patches are usually only used if you've already been taking other strong opioid painkillers.

Your doctor will work out how much fentanyl to give you depending on what dose of other opioids you've been taking. This is to reduce the risk of an overdose.

Who may not be able to use fentanyl

Fentanyl is not suitable for some people. To make sure it's safe for you, tell your doctor if you:

  • are not already regularly using strong opioid painkillers
  • have ever had an allergic reaction to fentanyl or any other medicine
  • have breathing difficulties such as asthma or a lung condition
  • are addicted to alcohol or are a heavy drinker
  • have a head injury
  • have a condition that causes fits or seizures
  • have an irregular heartbeat (arrhythmia)
  • have adrenal gland problems
  • have kidney or liver problems
  • have an enlarged prostate
  • have low blood pressure (hypotension)
  • are trying to get pregnant, are already pregnant or breastfeeding

View the original NHS website page ↗. Refreshed 19 August 2026.

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