This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.
Common side effects of lansoprazole
These common side effects of lansoprazole may happen in more than 1 in 100 people. There are things you can do to help cope with them:
Headaches
Make sure you rest and drink plenty of fluids. It's best not to drink too much alcohol. Ask your pharmacist to recommend a painkiller.
Headaches usually go away after the first week of taking lansoprazole. Talk to your doctor if they do not go away or are severe.
Feeling or being sick (nausea or vomiting)
Stick to simple meals and do not eat rich or spicy food.
If you're being sick, try small frequent sips of water to avoid dehydration. Signs of dehydration include peeing less than usual or having strong-smelling pee.
If you take the combined pill or progestogen-only pill and you're being sick, your contraception may not protect you from pregnancy. Check the pill packet for advice.
Diarrhoea
Drink lots of fluids, such as water or squash, to avoid dehydration. Signs of dehydration include peeing less than usual or having dark, strong-smelling pee. Do not take any other medicines to treat diarrhoea without speaking to a pharmacist or doctor.
If you take the combined pill or progestogen-only pill and you have severe, watery diarrhoea or diarrhoea that lasts for more than 24 hours, your contraception may not protect you from pregnancy. Check the pill packet for advice.
Stomach pain
Try to rest and relax. It can help to eat and drink slowly and have smaller and more frequent meals. Putting a heat pad or covered hot water bottle on your stomach may also help. If you are in a lot of pain, speak to your pharmacist or doctor.
Constipation
Get more fibre into your diet such as fresh fruit, vegetables and cereals, and drink plenty of water. Try to exercise more regularly, for example, by going for a daily walk or run.
Farting
Try not to eat foods that cause wind like lentils, peas, beans and onions. It might also help to eat smaller and more frequent meals, eat and drink slowly, and exercise regularly. Some pharmacy remedies, such as simeticone, may help relieve the symptoms of wind.
Itchy or mild rash
It may help to take an antihistamine which you can buy from a pharmacy. Check with the pharmacist to see what type is suitable for you.
Feeling dizzy or tired
If lansoprazole makes you feel dizzy or tired, stop what you're doing and sit or lie down until you feel better. Do not drive, cycle or use tools or machinery if you're feeling tired. Do not drink alcohol as it will make you feel worse.
Dry mouth or throat
Try chewing sugar-free gum or sucking sugar-free sweets.
Talk to a doctor or pharmacist if the advice on how to cope does not help and a side effect is still bothering you or does not go away.
View the original NHS website page ↗. Refreshed 19 August 2026.
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