This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.
Prochlorperazine is an anti-sickness medicine. It can help stop you feeling or being sick (nausea or vomiting).
You can take prochlorperazine to treat:
- sickness in pregnancy
- feeling dizzy or a spinning sensation (vertigo)
- motion sickness
- feeling sick due to migraines
- sickness caused by general anaesthetics after surgery
- sickness caused by cancer treatment or taking other medicines
- problems with balance such as Ménière's disease
Prochlorperazine is occasionally used to treat anxiety.
It comes as tablets that you swallow and tablets that dissolve in your mouth. It can also be given as an injection, but this is usually done in hospital.
Prochlorperazine tablets are available on prescription. You can also buy tablets in a pharmacy without a prescription to treat nausea and vomiting, but only if you've been previously diagnosed with migraines and are 18 years old or over.
View the original NHS website page ↗. Refreshed 19 August 2026.
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